Vanhu vazhinji vanoziva Parkinson's uye Alzheimer's. Chirwere cheParkinson chirwere chakajairika neurodegenerative. Inowanzoonekwa kune vakwegura. Avhareji yezera rekutanga inosvika makore makumi matanhatu. Vechidiki vane kutanga kwechirwere cheParkinson vari pasi pemakore makumi mana havawanzoitiki. Kuwanda kwePD pakati pevanhu vanopfuura makore makumi matanhatu neshanu muChina ndeye 1.7%. Varwere vazhinji vane chirwere cheParkinson vanowanzoitika, uye vasingasviki 10% yevarwere vane nhoroondo yemhuri. Kunyanya kukosha kwepathological shanduko muchirwere cheParkinson ndiko kuderera uye kufa kwedopaminergic neurons mu substantia nigra yepakati pebrain. Chikonzero chaicho chekuchinja kwechirwere ichi hachisati chanyatsojeka. Genetic factor, zvakatipoteredza, kuchembera, uye oxidative kusagadzikana zvese zvingave zvakabatanidzwa mukuderera uye kufa kwePH dopaminergic neurons. Zviratidzo zvaro zvekliniki zvinonyanya kusanganisira kuzorora kwekudengenyeka, bradykinesia, myotonia uye postural gait disturbance, nepo varwere vangave vachiperekedzwa nezviratidzo zvisiri zvemotokari zvakadai sekuora mwoyo, kuvimbiswa uye kukanganisa kurara.
Dementia, inozivikanwawo sechirwere cheAlzheimer, chirwere chinoenderera mberi neurodegenerative chine kutanga kusinganzwisisike. Mumakiriniki, inotaridzwa nedementia yakajairwa, yakadai sekukanganisa ndangariro, aphasia, apraxia, agnosia, kukanganisa kwehunyanzvi hwekuona, kusashanda zvakanaka kwehutungamiriri, uye shanduko muhunhu nemafambiro. Vaya vanotanga vasati vasvitsa makore 65 vanonzi chirwere cheAlzheimer; avo vanotanga mushure memakore makumi matanhatu nemashanu vanonzi Alzheimer's.
Zvirwere zviviri izvi zvinowanzotambudza vakwegura uye zvinoita kuti vana vazvidye mwoyo zvikuru. Naizvozvo, nzira yekudzivirira kuitika kwezvirwere zviviri izvi yagara iri hotspot yekutsvagisa yevadzidzi. China inyika huru yekugadzira tii nekunwa tii. Pamusoro pekuchenesa mafuta uye kubvisa girizi, tii ine bhenefiti isingatarisirwi, ndiko kuti, inogona kudzivirira chirwere cheParkinson uye chirwere cheAlzheimer.
Tii yegirini ine chinhu chakakosha chinoshanda: epigallocatechin gallate, inova ndiyo inonyanya kushanda musanganiswa weti polyphenols uye ndeye katechini.
Zvidzidzo zvakawanda zvakaratidza kuti epigallocatechin gallate inodzivirira tsinga kubva mukukuvadzwa muzvirwere zveurourodegenerative. Zvidzidzo zvemazuva ano epidemiological zvakaratidza kuti kunwa tii kwakabatana zvisina kunaka nekuitika kwezvimwe zvirwere zveurourodegenerative, saka zvinofungidzirwa kuti kunwa tii kunogona kumisa mamwe endogenous ekudzivirira nzira mumaseru neuronal. EGCG inewo maitiro ekugadzirisa, uye basa rayo rekudzivirira rinonyanya kuwirirana nekubatana kwe γ-aminobutyric acid receptors. Kune vanhu vane HIV, hutachiona-induced neurodementia inzira ye pathogenic, uye zvidzidzo zvenguva pfupi zvakaratidza kuti EGCG inogona kuvhara iyi pathological process.
EGCG inonyanya kuwanikwa mu green tea, asi kwete mu black tea, saka kapu yetii yakajeka mushure mekudya inogona kubvisa mafuta uye kubvisa greasy, iyo ine utano hwakanaka. EGCE yakatorwa kubva mugirini tii inogona kushandiswa mune zvehutano zvigadzirwa uye zvekudya zvinowedzera, uye chishandiso chikuru chekudzivirira zvirwere zvataurwa pamusoro apa.
Nguva yekutumira: Kubvumbi-06-2022