Berberine: Mashandisirwo, Mabhenefiti, Zvekuwedzera uye Madivi Emhedzisiro

Berberine ine nhoroondo refu yekushandiswa mune zvechivanhu mishonga masisitimu, sengeAyurvedauye East Asia mushonga. Ikemikari inovava-inonaka inobva mumiti yakasiyana-siyana, yakadai se hydrastis canadensis (goldenseal), coptis chinensis (coptis kana goldenthread) uye berberis vulgaris (barberry). Tsvagiridzo inoratidza kuti berberine inogona kunge ine antimicrobial uye mishonga inorwisa mabhakitiriya, pamwe nemhedzisiro yakanaka pametabolism, asi mimwe miedzo yekiriniki inodiwa kusimbisa izvi zvakanaka.

Berberine inogona zvakare kuve neakawanda mabhenefiti emuviri uye zviitiko zvemishonga muchiropa, itsvo, moyo uye uropi, zvichikwanisa kupa imwe metabolic rutsigiro. Semuenzaniso, berberine inomutsa enzyme AMP-activated protein kinase, iyo tsvakurudzo inoratidza kuti inobatsira kugadzirisa metabolism, kushanda kwesero uye simba remasimba.

Berberine inonyanya kushandiswa kubatsirashuga shoma yeropa, kuvandudza hutano hwemwoyo, kuderedza oxidative kusagadzikana uyekuderedza cholesterol, pamwe chete nemigumisiro yayo yekudzivirira-manyoka, anti-inflammatory uye anti-cancer, anodaro Heather Zwickey, Ph.D, purofesa we immunology paNational University of Natural Medicine muPortland, Oregon.

Berberine inowanzowanikwa mune capsule fomu, asi zvakare yakagadzirwa semadonhwe eziso uye gels kune akasiyana siyana ekuzvimba mamiriro eganda, maziso kana majoini.

Miti mizhinji nemishonga ine berberine yave ichishandiswa mukurapa kwezviuru zvemakore, asi tsvakiridzo yakawanda inodiwa kuti tinzwisise maitiro ekomboni uye mhedzisiro yenguva refu. Nezvakataurwa, tsvakiridzo inoratidza kuti inogona kubatsira hutano hwemunhu munzira dzakawanda.

Inogona Kubatsira Kudzikisa Ropa Shuga uye Kudzivirira Insulin Resistance

Ongororo ye2022 mukatiMamorekuruinoratidza berberine inogona kubatsirakuderedza ropa reglucosenokuti inowedzera kugadzirwa kwe insulini uye inovandudza insulin senitivity, kunyange zvazvo tsvakurudzo yakawanda ichidiwa kuti unzwisise zvizere izvi zvinokonzerwa[1].

Inogona Kubatsira Kudzikisa Cholesterol

Tsvagiridzo inoratidza berberine inogona kuve nemhedzisiro yakanakaLDL cholesteroluye cholesterol yakazara, kunyange zvazvo mimwe miedzo yekiriniki ichidiwa kuti unzwisise chirevo chehutano ichi zvachose.

Inogona Kuvandudza Cardiovascular Health

Berberine inogona kuva nemigumisiro yakanaka pamakumbo emwoyo, kunyanya mumamiriro ezvinhu eischemia (kusakwana kweropa rekupa), nekukwanisa kuvandudza simba remhasuru yemwoyo, kuderedza kuzvimba, kuderedza oxidative stress, kuderedza BP uye kuwedzera kubuda kwemwoyo.

Inogona Kuve neAnti-Inflammatory Effects

Berberine inonzi alkaloid inovava inopa systemic anti-inflammatory effects, anodaro Alicia McCubbins, chiremba naturopathic anogara muVancouver, Washington. Izvi zvivakwa zvinogona kubatsira maitiro ese emagetsi, akadai seanogona kubatsira mukudzivirira atherosclerosis, Type 2 chirwere cheshuga, kufutisa uye matambudziko emoyo. Berberine's anti-inflammatory properties yakadzidzwa kwenguva yakareba, asi maitiro ayo ekuita haasati anzwisiswa, kuratidza kudiwa kwekuwedzera tsvakurudzo.

Inogona Kuve neAntioxidant Properties

A 2018 wongororo muFrontiers muPharmacologyinogumisa kuti berberine's antioxidant effects inofananidzwa neiyo yevhitamini C, iyo ine simba zvikuru antioxidant[2]. Zvinhu zvakaita sevhitamini C uye berberine zvinoshanda sema antioxidants kubatsira kudzivirira kukuvadzwa kwemahara radicals kunogona kukonzera kumasero.

Inogona Iine Antibacterial uye Antimicrobial Properties

"Berberine ine astringent properties uye inoonekwa seyakasikwa antimicrobial ine simba rekubvisa mabhakitiriya, zvipembenene uye fungi / candida," anogovera Dr. McCubbins. Aya antimicrobial properties anogona kubatsira kuvandudza mamwe mamiriro, akadai seacutemanyoka, dysentery, jaundice uye zvirwere zvemukati, kunyange tsvakurudzo yakawanda ichidiwa kutsigira izvi zvirevo. Kana munhu achitenda kuti ane hutachiona hwemhando ipi neipi, vanofanirwa kubvunza mutarisiri wavo wehutano kuti vatariswe zvakafanira uye kurapwa vasati vatora berberine kana chero imwe yekuwedzera.

Inogona Kuvandudza Utano Hwekudya

Berberine inogona kubatsira kunetseka kwekugaya, senge kuvimbiswa uyechirungurira, maererano naDr. McCubbins. "Aya alkaloids anogona kupa zvikomborero zvakavimbiswa kune gut-brain connection," anowedzera, achisimbisa kukosha kwekubatana pakati pekudya, mafungiro uye hutano hwose.

Inogona Kutsigira Weight Loss uye Weight Management

Berberine inogona kubatsira kuderedza mafuta uye glucose kuchengetedza nekuvandudza metabolic maitiro, sekuparara kwe lipids (mafuta) uye shuga, tsvagiridzo inoratidza. Berberines 'yakanaka maitiro pane gut microbiome inogona zvakare kuve chinhu chakakosha mukutsigira kwayo uremu manejimendi.

Inogona Kuvandudza Zviratidzo zvePolycystic Ovarian Syndrome (PCOS) uye Ovulation

Maererano nekuongorora muMamorekuru, kutora 1,500 milligrams yeberberine pazuva kwemwedzi mitatu yakaderedza mazinga e testosterone akakwirira muvakadzi vanePCOS[3]. Chirwere ichi chinogona kusanganisira mazinga ehomoni asina kujairika uye zvichikonzera kusaenzana, zvichikonzera nyaya senge madiki cysts pamaovha kana kuenda kumwedzi kusiri kujairika. Nyanzvi dzinotendawo kuti berberine inovandudza insulin kuramba, inova chinhu chakajairika chePCOS. Zvisinei, vatsvakurudzi vanokurudzira kumwe kuedzwa kwekiriniki kunodiwa kusimbisa iyi mhedzisiro yeberberine, kusanganisira kureba kwekurapa uye kurapa dosing.

 

Nzira yekutora Berberine?

Berberine supplements inowanikwa mune capsule, piritsi kana tincture fomu, ichibvumira chaiyo dosing uye nyore kushandisa. Capsules inogona kudiwa kune vatengi vazhinji vakapihwa kuravira kwayo kwakanyanya, anotsanangura Dr. McCubbins. "Berberine inowanzotorwa senge tonic yekugaya 5 kusvika 30 maminetsi vasati vadya. Berberine inovava izvo zvinomutsa muto wemudumbu kuti ushande zvakanaka kugaya,” anoenderera mberi.

Berberine Dosage

Vanhu vanofanira kubvunza mutarisiri wehutano kana kuti herbalist kuti vakurukure zvakarurama dosing (iyo isina kuenzaniswa), uye kuverenga mirayiridzo yemugadziri, anodaro Dr. Zwickey. “Inowanzoonekwa seyakakotsekana mumiyedzo [yezuva nezuva] ye[isingapfuuri] magiramu maviri. Kuti [kuwana mhedzisiro yakanaka], munhu angangoda kushandisa giramu rimwe chete (1000 milligrams) pazuva. Mishonga yakawanda [ine] 500 milligrams per capsule, saka mumwe munhu angada kunwa [anenge maviri] capsules pazuva," anoenderera mberi.

Berberine dosage inogona kuenderana nezvinangwa zvehutano hwemunhu. Nezve shuga yeropa, 2019 yakarongeka ongororo uye meta-kuongorora muneEndocrine Journalakawana kutora pasi pe2 gramu yeberberine pazuva kwemwedzi mitatu zvakakanganisa mazinga eglucose eropa revatori vechikamu vane chirwere cheshuga chechipiri.[4].

Zvichakadaro, ongororo yetsvakiridzo iripo muComplementary Therapies muClinical Practiceyakaongorora mhinduro yedosi yeberberine yakatorwa kune vanhu vane kufutisa uye vachitsvaga huremu hwekutonga, vakawana kuti dosi ye500 milligrams inotorwa katatu pazuva yakakonzera kudzikira.body mass index (BMI), kutenderera kwechiuno uye uremu hwemuviri[5].

Berberine Side Effects

Berberine supplements inogona kuva nemimwe migumisiro, kusanganisira manyoka, kuputika kwemudumbu uye musoro, anodaro Dr. McCubbins.

"Berberine iri kuwedzera mukurumbira uye kutengeswa zvakanyanya kunharaunda yekurasikirwa nehuremu," anoenderera mberi. "Ngwarira uye bvunza chiremba wenaturopathic nezve [mashandisirwo] ekurapa [yeberberine usati waidya]."

Kunyange zvazvo berberine inowanzotenderwa zvakanaka, inogona kukonzera kurwadziwa kwepamuviri uye kuputika, kuvhara, manyoka, flatulence, kushungurudza uye kurutsa, anowedzera Dr. Zwickey.

Berberine Yakachengeteka here?

Chinhu chikuru chekuchengetedzwa kweberberine ndechokuti inogona kuwirirana nemishonga yakawanda, anodaro Dr. Zwickey. Iyo yakanyanya kusimba yekudyidzana ndeye cyclosporine, immunosuppressive mushonga unoshandiswa mushure mekuisirwa nhengo uye kubatsira kubata autoimmune mamiriro senge.rheumatoid arthritis, sezvo berberine inowedzera kuwedzera kwe cyclosporine muropa, anotsanangura.

Zvisinei nekuti munhu anotora berberine seyakagadzirwa yakamira yega yekuwedzera kana mune yakazara herbl fomati, zvakakosha kutevedzera inokurudzirwa dosi mirairo inopihwa nemugadziri wechigadzirwa kana nyanzvi yezvehutano. Berberine inorambidzwa kuvana, pamwe chete nevanhu vane pamuviri uye vanoyamwisa, anodaro Dr. Zwickey.

Chii Chaunofanira Kufunga Kana Uchitenga Berberine?

Nekuti vazhinji vanogadzira vanochenesa berberine kubva muchirimwa, yechitatu-bato murabhoritari kuongororwa kuti ndiani berberine, simba, kunaka uye kuchena kwakakosha, anodaro Dr. Zwickey. "Mumwe anofanirwa kunge achinyanya kukoshesa kutsvaga kwekuwedzera kubva kune chiremba-giredhi yekuwedzera kambani kuti ave nechokwadi chevechitatu-bato kuyedzwa kubva kumakambani anoremekedzwa uye kuvimbiswa kwemhando ye [iyo] yakanakisa [dosing] mutemo," anowedzera Dr. McCubbins.

Zvakakoshawo kuve nechokwadi chekuti berberine inowanikwa zvakachengetedzeka, sekureva kwaDr. McCubbins. "Goldenseal, kunyangwe iri sosi yakanaka yeberberine, iri mungozi. Makambani ane mukurumbira anowedzera anoziva nezve [nyaya] iyi,” anotsanangura kudaro. Mazhinji ekuwedzera mavara anotsanangura kubva kune izvo herbs iyo berberine inotorwa.

Sezvo berberine iri kushaya zvidzidzo zvekuchengetedza kwenguva refu, munhu anofanirwa kubvunzana nemupi wehutano asati awedzera berberine kune yavo yekuwedzera regimen kuti vaone kuti yakakodzera uye yakachengeteka kune avo akasiyana ehutano zvavanoda. Kuti udzidze zvakawanda nezve berberine inogona kubatsira pautano, taura nanaturopathic chiremba, certified herbalist kana acupuncturist.